Welcome to 149 Skyline Avenue, located in the heart of The Uplands, one of London's most prestigious and family-friendly neighborhoods. Known for its top-rated schools and green spaces. This is a highly sought-after location for growing families. This custom-built two-story home offers 2616 sq. ft. of above grade living space and sits on a rare huge 0.267 ac lot. The main floor features 9-foot ceilings and a beautifully updated kitchen with central island, stainless steel appliances, quartz countertops, tile backsplash, and gas stove. A main floor den or study room, formal denning room combined with a living room with cathedral ceilings. The fantastic sized open concept kitchen and family room with a fireplace across the rear of the home overlooking a very private yard facing the afternoon sun for those barbeque days and family times. Upstairs, you'll find a large primary suite with a 5-piece ensuite and walk-in closet, and 3 other well-sized bedrooms. The finished basement includes exercise area, recreation area and a wet bar. There is plenty of space for 2 more additional bedrooms to potential development. The driveway fits 4 cars, plus a 2-car garage, offering parking for 6. Recent updates include a newer AC (2023), Washer and Refrigerator (2024), kitchen counter top (2026), paint (2026). Laminate flooring throughout in the basement, and hardwood floor in the main floor, second floor hall and primary bedroom as well. Located within the catchment of Jack Chambers PS, Mother Teresa CSS, and A.B. Lucas SS, and just minutes from Western University, University Hospital, Masonville Mall, parks, and transit-this home delivers the space, setting, and location you've been waiting for.